Mitochondrial dysfunction, alternans, and arrhythmias
نویسندگان
چکیده
منابع مشابه
Mitochondrial dysfunction, alternans, and arrhythmias
It seems already like a long time ago that we used to think about heart failure as a problem in which mitochondria and energy were not involved. Energy has been for so long granted in the mind of mainstream electrophysiologists, but not anymore. Although energy can be taken for granted under normal conditions, this is not the case in heart failure where dysfunctional mitochondria, lack of subst...
متن کاملAlternans and arrhythmias: from cell to heart.
The goal of systems biology is to relate events at the molecular level to more integrated scales from organelle to cell, tissue, and living organism. Here, we review how normal and abnormal excitation-contraction coupling properties emerge from the protein scale, where behaviors are dominated by randomness, to the cell and tissue scales, where heart has to beat with reliable regularity for a li...
متن کاملP8: Temporal Lobe Epilepsy and Mitochondrial Dysfunction
لطفاً به چکیده انگلیسی مراجعه شود.
متن کاملT wave alternans and ventricular arrhythmias in arterial hypertension.
Patients with a positive microvolt-level T wave alternans (TWA) are characterized by an increased risk of ventricular tachyarrhythmias. Arterial hypertension leads to an increase of sudden cardiac death risk, particularly if left ventricular hypertrophy is present. The aim of this study was to investigate the value of TWA in patients with arterial hypertension. Fifty-one consecutive patients we...
متن کاملT-wave alternans and the susceptibility to ventricular arrhythmias.
T-wave alternans (TWA) reflects beat-to-beat fluctuations in the electrocardiographic T-wave, and is associated with dispersion of repolarization and the mechanisms for sudden cardiac arrest (SCA). This review examines the bench-to-bedside literature that, over decades, has linked alternans of repolarization in cellular, whole-heart, and human studies with spatial dispersion of repolarization, ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Physiology
سال: 2013
ISSN: 1664-042X
DOI: 10.3389/fphys.2013.00083